Short Article An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells Graphical Abstract

Source URL: www.umassmed.edu

Discovery of the Mechanism by which Mitochondria are Eliminated from Red Blood Cells and the Involvement of Alternative Autophagy DNA Demethylation-Dependent Regulation of Hepatic Lipid Metabolism Shigeomi Shimizu

Source URL: www.tmd.ac.jp

PL-ISSNprint), ISSNonline) Folia Biologica (Kraków), vol), No 2 Ó Institute of Systematics and Evolution of Animals, PAS, Kraków, 2014

Source URL: www.isez.pan.krakow.pl

• DNA
• Posttranslational modification
• Molecular genetics
• Gene expression
• Methylation
• DNA methylation
• Reprogramming
• Cellular differentiation
• DNA demethylation
• Genetics
• Biology
• Epigenetics

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

Source URL: www.nature.com

• Stem cells
• Developmental biology
• Genomics
• Biotechnology
• Cellular differentiation
• Mitochondrial DNA
• Induced pluripotent stem cell
• DNA methylation
• Methylated DNA immunoprecipitation
• Biology
• Genetics
• Epigenetics

DNA demethylation activity over time and safety of 3 different dose-escalation regimens of SGI-110, a novel subcutaneous (SQ) hypomethylating agent (HMA), in the treatment of relapsed/refractory patients with MDS and AML

Source URL: astx.com

• Pharmacology
• Azacitidine
• lactams
• Chemistry
• Decitabine
• Hypomethylating agent
• Nucleosides
• Triazines
• Medicine

Study of the correlation of baseline biomarkers and DNA demethylation to clinical responses in a phase 1/2, randomized study of SGI-110, a novel subcutaneous hypomethylating agent in the treatment of relapsed/refractory

Source URL: astx.com

• Medicine
• Epigenetics
• Biology
• Acute leukemia
• Myeloid leukemia
• Azacitidine
• Acute myeloid leukemia
• Hypomethylating agent
• Decitabine
• Oncology
• Nucleosides
• Triazines

Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment

Source URL: demo.openrepository.com

• Molecular biology
• DNA
• Mutation
• Posttranslational modification
• DNA methylation
• DNA methyltransferase
• Methylation
• Carcinogenesis
• DNA demethylation
• Biology
• Genetics
• Epigenetics

2014_SGI-110_poster_ASCO_abst_7030_Griffiths-draft_v6

Source URL: astx.com

• Myeloid leukemia
• Nucleosides
• Triazines
• Acute myeloid leukemia
• Azacitidine
• Hypomethylating agent
• Decitabine
• DNA demethylation
• Leukemia
• Oncology
• Medicine
• Acute leukemia

Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells

Source URL: www.epigeneticsandchromatin.com

• DNA
• Molecular genetics
• Molecular biology
• 5-Hydroxymethylcytosine
• DNA demethylation
• DNA methylation
• 5-Methylcytosine
• MECP2
• CpG site
• Biology
• Genetics
• Epigenetics

letters to nature breaks induced at ectopic transcription units 21 activated by demethylation. The data presented here show that Dnmt3L is required for heritable silencing of retrotransposons in male germ cells. Temporar

Source URL: web.mit.edu

• Molecular biology
• Molecular genetics
• Transcription factors
• Promoter
• Phylogenetic footprinting
• DNA methylation
• Ridge
• DNA binding site
• Regulation of gene expression
• Biology
• Gene expression
• DNA